Clinical Gastroenterology Vol.26 No.5(6)

Theme Benign to Low-malignant Pancreatobiliary Lesionst
Title Xanthogranulomatous Cholecystitis
Publish Date 2011/05
Author Hideyoshi Toyokawa Department of Surgery, Kansai Medical University
Author Masanori Kon(A-Hon Kwon) Department of Surgery, Kansai Medical University
[ Summary ] Xanthogranulomatous cholecystitis (XGC) is an uncommon variant of chronic cholecystitis and destructive inflammatory processes of the gallbladder. The inflammation often extends into adjacent organs, and therefore, XGC may be confused with advanced gallbladder carcinomas. Diagnosis is usually possible only after pathological examination, because radiologic findings are nonspecific. Laparoscopic cholecystectomy is frequently unsuccessful with a relatively high conversion rate to open cholecystectomies because of associated pathologic features. Therefore, detailed radiological and histological exploration is necessary to avoid excess surgery and misdiagnosis. As a result, intra-operative frozen section histology is helpful to differentiate XGC from gallbladder carcinoma.
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