Clinical Gastroenterology Vol.26 No.4(7)

Theme Diversified Modalities of Liver Metastasis Treatment
Title Volume Reduction Surgery with MCN and Hepatic Resection for Liver Metastases Resulting from Breast Cancer
Publish Date 2011/04
Author Yuko Takami Center for Liver Diseases & Clinical Research Institute, National Hospital Organization Kyushu Medical Center
Author Yoshiyuki Wada Center for Liver Diseases & Clinical Research Institute, National Hospital Organization Kyushu Medical Center
Author Hiroki Takahashi Breast Care Center, National Hospital Organization Kyushu Medical Center
Author Teruhiko Fujii Breast Care Center, National Hospital Organization Kyushu Medical Center
Author Koji Ikejiri Center for Gastroenterology, National Hospital Organization Kyushu Medical Center
Author Hideki Saitsu Center for Liver Diseases & Clinical Research Institute, National Hospital Organization Kyushu Medical Center
[ Summary ] From July, 1994 to November, 2009, we surgically treated 27 cases of liver metastases resulting from breast cancer. Resection and/or microwave coagulo-necrotic therapy (MCN) were performed. After these operations, chemotherapy and/or endocrine therapy were also given to the patients. The 1, 3, and 5-year survival rates for all patients after their first surgical liver treatment were 96.2 %, 60.2 %, and 51.0 %.
In general, breast cancer metastases into the liver are rarely indicated for surgical treatment. However, we have recently encountered reports that liver resection is a useful procedure to improve the poor prognoses for liver metastases of mammary origin. From related literature and our experience, we believe that surgical treatments such as reduction surgery should be considered to be beneficial options for liver metastases arising from breast cancer. In particular, MCN is a useful procedure for multiple liver metastases.
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