| Theme | Diversified Modalities of Liver Metastasis Treatment | |
|---|---|---|
| Title | Recent Advances in Multimodal Treatment for Gastric Cancer with Liver Metastases | |
| Publish Date | 2011/04 | |
| Author | Norihito Wada | Department of Surgery, School of Medicine, Keio University |
| Author | Kazumasa Fukuda | Department of Surgery, School of Medicine, Keio University |
| Author | Rieko Nakamura | Department of Surgery, School of Medicine, Keio University |
| Author | Tsunehito Takahashi | Department of Surgery, School of Medicine, Keio University |
| Author | Takashi Ohyama | Department of Surgery, School of Medicine, Keio University |
| Author | Hiroya Takeuchi | Department of Surgery, School of Medicine, Keio University |
| Author | Yoshiro Saikawa | Department of Surgery, School of Medicine, Keio University |
| Author | Yuko Kitagawa | Department of Surgery, School of Medicine, Keio University |
| [ Summary ] | The prognosis for patients with liver metastases which have progressed from gastric cancer is dismal. However, there are many treatment modalities, with hepatectomy playing an important role in curative management of metastatic disease. Between 1991 and 2008, 83 patients with liver metastasis arising from gastric cancer were cared for in our institution. Seven of these patients (8.4 %) survived for 3 years. Five outof 7 patients received hepatectomies as the initial treatment for their hepatic tumors. The other 2 patients had systemic chemotherapy followed by liver resection. Hepatectomy may be an essential step in achieving curative outcomes in multimodal treatment of particular patients with hepatic involvement, leading to advanced gastric cancer. Further investigation of hepatectomy as a curative approach for metastatic tumors resulting from gastric cancer is warranted to clinically establish causative links. | |