| Theme | Hilar and Intrahepatic Cholangiocarcinoma | |
|---|---|---|
| Title | Pathology of Hilar and Intrahepatic Cholangiocarcinoma | |
| Publish Date | 2011/12 | |
| Author | Yasuni Nakanuma | Department of Human Pathology, Kanazawa University Graduate School of Medicine |
| Author | Motoko Sasaki | Department of Human Pathology, Kanazawa University Graduate School of Medicine |
| Author | Yasunori Sato | Department of Human Pathology, Kanazawa University Graduate School of Medicine |
| Author | Kenichi Harada | Department of Human Pathology, Kanazawa University Graduate School of Medicine |
| Author | Hiroko Ikeda | Pathology Diagnosis Service Section, Kanazawa University Hospital |
| [ Summary ] | Hilar cholangiocarcinoma and intrahepatic cholangiocarcinoma are reviewed in respect to anatomical location. Hilar cholangiocarcinoma is related to biliary tract carcinoma and intrahepatic cholangiocarcinoma of the perihilar area. They resemble each other grossly and histologically. They may be included in a unified concept of perihilar cholangiocarcinoma. Intraductal growing type biliary neoplasms, which occur in the intrahepatic and extrahepatic bile ducts, exhibit luminal dilatation and not infrequently mucin secretion. This type of neoplasm resembles mucinous cystic neoplasms of the hepatobiliary system. However, in the latter, ovarianlike stroma expressing progesterone and estrogen receptors are present. Intrahepatic cholagiocarcinoma, of the peripheral type, exhibit a mass-forming pattern, which is grossly different from perihilar intrahepatic cholangiocarcinoma. | |