| Theme | Reappraisal of Colorectal Protruded and Flat Lesions Which are Encountered During Endoscopy | |
|---|---|---|
| Title | Chromoendoscopic Imaging and Magnifying NBI for Colorectal Lesion Examination | |
| Publish Date | 2011/11 | |
| Author | Yoshiki Wada | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Shin-ei Kudo | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Masashi Misawa | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Kunihiko Wakamura | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Nobunao Ikehara | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Shigeharu Hamatani | Department of Pathology, Showa University Northern Yokohama Hospital |
| Author | Hiroshi Kashida | Department of Gastroenterology, Kinki University Hospital |
| [ Summary ] | Chromoendoscopy with indigo-carmine or crystal violet dye is currently used for tissue characterization and differential diagnosis. Magnifying chromoendoscopy provides an accurate and immediate assessment of the histology of colorectal tumors. VN and VI high-grade pit patterns are considered to be massively submucosal invasive cancer (SMm). Lesions with VI high-grade was defined as destroyed pits. Magnifying NBI may indicate irregular patterns, which are characteristic of protruding or flat-elevated cancers. On the other hand, sparse patterns are unique to depressed cancers. Both NBI and chromoendoscopy can be useful for distinguishing between slightly submucosal invasive cancer (SMs) and SMm. In the diagnosis of SMm, pit pattern diagnoses are slightly superior to vascular pattern diagnosis. It is desirable to perform chromoendoscopy in addition to NBI for distinguishing between SMs and SMm and determining treatment selection, endoscopic or surgically. | |