Clinical Gastroenterology Vol.26 No.10(9)

Theme Current Status of Uprising Strategy for Esophageal Cancer Treatment
Title Endoscopic Treatment for Residual or Recurrent Esophageal Cancer after Chemoradiotherapy
Publish Date 2011/09
Author Shinya Kondo Department of Endoscopy, Aichi Cancer Center Hospital
Author Yasumasa Niwa Department of Endoscopy, Aichi Cancer Center Hospital
Author Masahiro Tajika Department of Endoscopy, Aichi Cancer Center Hospital
Author Hiroki Kawai Department of Endoscopy, Aichi Cancer Center Hospital
Author Takafumi Ando Department of Gastroenterology, Nagoya University Graduate School of Medicine
Author Hidemi Goto Department of Gastroenterology, Nagoya University Graduate School of Medicine
[ Summary ] Radiation (RT) or chemoradiotherapy (CRT) is one of the treatments for esophageal squamous cell carcinoma. However, determining the most effective treatment for residual or recurrent tumors after RT or CRT is a problem which continues to confront us. In cases where residual or recurrent tumors are detected in superficial layers, endoscopic treatment is considered to be a curative option. Endoscopic mucosal resection (EMR) for residual or recurrent tumors after RT or CRT was performed on 46 patients (76 lesions). Seventy-four lesions were treated with EMR using a cap fitted endoscope (EMR-C). The enbloc resection rate was 80.3 % and the curative resection rate was 69.7 %. Complications occurred in six patients, one with postoperative bleeding and five with postoperative strictures. All patients were cured through additional endoscopic treatment.
In conclusion, EMR-C may be an effective and safe treatment for residual or recurrent tumors after RT or CRT administration for esophageal cancer patients.
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