Clinical Gastroenterology Vol.26 No.10(4)

Theme Current Status of Uprising Strategy for Esophageal Cancer Treatment
Title Treatment Strategies for Esophageal Cancer Based on Surgical Outcomes
Publish Date 2011/09
Author Shigeru Lee Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine
Author Harushi Osugi Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine
Author Satoru Kishida Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine
Author Masato Okawa Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine
Author Ken Gyobu Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine
Author Eijiro Edagawa Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine
[ Summary ] Esophageal cancer is the most challenging malignant gastrointestinal neoplasm. Patients with this condition have a five year survival rate of 25 %. Improvements in survival have been attempted with combined modality treatments. The Japanese guidelines for diagnosis and treatment of esophageal cancer indicate the treatment of choice for resectable conditions should be esophagectomy. In light of the results of the JCOG9907 study, a combination of neoadjuvant chemotherapy combined with surgery is accepted as the standard treatment for cStage II/III disease. With the goal of reducing invasiveness, thoracoscopic esophagectomy has been rapidly adopted. 20 % of esophagectomies are performed thoracoscopically. In our institution, 5-year survival rates after thoracoscopic surgery were 69 % and 52 % for pStage II and III, respectively. We experienced no major surgical complications. Thoracoscopic esophagectomy is expected to become a popular treatment securing the principle of safety.
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