Clinical Gastroenterology Vol.26 No.1(7)

Theme Pancreatic Cancer : Up-to-date
Title EUS for Diagnosis of Pancreatic Disease
Publish Date 2011/01
Author Takamitsu Komaki Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Masayuki Kitano Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Hiroki Sakamoto Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Hajime Imai Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Ken Kamata Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Tsuyoshi Miyata Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
Author Masatoshi Kudo Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kinki University School of Medicine
[ Summary ] The indications for endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for pancreatic lesions are as follows:differential diagnosis of benign and malignant lesions and characterization of neoplasms and cancer staging. The sensitivity, specificity and accuracy of EUSFNA for diagnosing pancreatic cancer are reportedly 80-90%, 100%, and 85-95%, respecitvely. The overall complication rate appears to be 0.5-2.5%.
Recently, second generation contrast agents for ultrasonography have been developed and contrast-enhanced harmonic imaging with EUS (CH-EUS) is now available. In a contrast-enhanced harmonic EUS study, using the ExPHD mode, pancreatic tumors were classified into four vascular patterns (avascular, hypovascular, isovascular and hypervascular).
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