Clinical Gastroenterology Vol.25 No.5(10)

Theme Vascular Disorder of Gastro-intestinal Tract
Title Diagnosis and Treatment of Blue Rubber Bleb Nevus Syndrome
Publish Date 2010/05
Author Yasuhiko Hamada Department of Endoscopy, Hiroshima University Hospital
Author Shinji Tanaka Department of Endoscopy, Hiroshima University Hospital
Author Shiro Oka Department of Endoscopy, Hiroshima University Hospital
Author Takayoshi Shishido Department of Gastroenterology, Hiroshima University Hospital
Author Hiroki Imagawa Department of Gastroenterology, Hiroshima University Hospital
Author Kazuaki Chayama Department of Gastroenterology, Hiroshima University Hospital
[ Summary ] Blue rubber bleb nevus syndrome (BRBNS) is a rare disease characterized by hemangioma of the skin and gastrointestinal (GI) tract. Since GI hemangioma often causes severe GI bleeding, it usually requires treatment. The primary procedures for GI hemangioma are surgical resection and endoscopic treatment. Because endoscopic treatment is safe and non-invasive, treatment is now performed for GI hemangioma. For endoscopic treatment of GI hemangioma with BRBNS, we recommend endoscopic sclerotherapy with polidocanol. This is because sclerotherapy with polidocanol is a safe and effective treatment. Another reason is that sclerothearpy is also relatively easy to use, when ballon endoscopy is performed.
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