Clinical Gastroenterology Vol.25 No.4(2)

Theme Algorithm for Diagnosis and Treatment of Liver Cancer
Title Integrated Staging System and Prognostic Expectation for Hepatocellular Carcinoma
Publish Date 2010/04
Author Shinya Morimoto Department of Surgery, The University of Tokushima
Author Mitsuo Shimada Department of Surgery, The University of Tokushima
Author Tohru Utsunomiya Department of Surgery, The University of Tokushima
Author Satoru Imura Department of Surgery, The University of Tokushima
Author Yuji Morine Department of Surgery, The University of Tokushima
Author Tetsuya Ikemoto Department of Surgery, The University of Tokushima
Author Hiroki Mori Department of Surgery, The University of Tokushima
Author Jun Hanaoka Department of Surgery, The University of Tokushima
[ Summary ] Various staging systems for hepatocellular carcinoma (HCC) have been employed. In 1985, the Okuda classification was initially introduced. Since then, CLIP score, BCLC staging, JIS score, Tokyo score, and modified JIS score have been initiated. Among these classifications, JIS score, which combines both the Child-Pugh classification and tumornode-metastasis stage, has provided a better stratification ability and prognostic predictive ability than other staging systems. However, no consensus has been obtained to incorporate the JIS score into the "RClinical Practice Guideline for HCCS". It may thus be necessary to create better staging systems for HCC by adopting other indicators, such as tumor markers.
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