| Theme | Update of PET Diagnosis for Cancer of Digestive Organs | |
|---|---|---|
| Title | Principle and Evaluation Method of PET and PET/CT | |
| Publish Date | 2009/03 | |
| Author | Akira Matsuura | PET Center, Dokkyo Medical University Hospital / Department of Gastroenterology, Dokkyo Medical University Hospital |
| Author | Kouji Murakami | PET Center, Dokkyo Medical University Hospital |
| Author | Hideyuki Hiraishi | Department of Gastroenterology, Dokkyo Medical University Hospital |
| [ Summary ] | Positron emission tomography (PET) is a novel functional imaging procedure which depicts the spatial distribution of labeled cellular metabolites. Glucose is the most biologically active molecule, thus the 18F marker fluorodeoxyglucose (FDG, glucose analogue) is widely used for PET scans. Due to its short half life, this radionuclide must be produced using a cyclotron at a radiochemistry laboratory close to the PET imaging facility. The recently developed PET/CT system is a device which combines the functional imaging data of PETs and the anatomic correlation produced by CTs, merging them into a powerful diagnostic tool. Moreover, PET/CT systems can reconstruct three dimensional images by using a multidetector-CTs. Although there is no significant difference between visual and semi-quantitative evaluations, FDG standardized uptake values (SUV) add another useful judgement tool to the range of diagnostic systems presently available. |
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