| Theme | Intestinal Mucosal Damage Induced by Drugs | |
|---|---|---|
| Title | Diagnosis and Treatment of Non-steroidal Antiinflammatory Drug-induced Small Bowel Ulcers | |
| Publish Date | 2009/12 | |
| Author | Naoyuki Nishimura | Department of Medicine, Division of Gastroenterology, Jichi Medical University |
| Author | Hironori Yamamoto | Department of Medicine, Division of Gastroenterology, Jichi Medical University |
| Author | Tomonori Yano | Department of Medicine, Division of Gastroenterology, Jichi Medical University |
| Author | Yoshikazu Hayashi | Department of Medicine, Division of Gastroenterology, Jichi Medical University |
| Author | Tomohiko Miyata | Department of Medicine, Division of Gastroenterology, Jichi Medical University |
| Author | Keijiro Sunada | Department of Medicine, Division of Gastroenterology, Jichi Medical University |
| [ Summary ] | Double-balloon endoscopy (DBE) and capsule endoscopy have revealed that non-steroidal anti-inflammatory drugs often(NSAIDs)-induce small bowel injuries. NSAIDs can cause a variety of abnormalities in the small intestine such as ulcerations, bleeding, and diaphragm-like strictures. Using DBE, 18 patients were diagnosed with NSAIDinduced enteropathy. NSAID-induced small bowel injuries showed a variety of patterns indicative of ulcerative lesions, which are observed in the ileum in many cases. The diaphragm-like strictures can be effectively and safely treated with balloon dilatation using DBE. | |