Clinical Gastroenterology Vol.24 No.11(3-1)

Theme Clinical Problems after Gastrectomy
Title Carcinogenesis in Remnant Stomachs
Publish Date 2009/10
Author Nobuyuki Shimizu Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo
Author Yasuyuki Seto Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo
[ Summary ] Because of improvements in the diagnosis and treatment of stomach cancer, carcinogenesis in remnant stomachs has become one of the most serious complications for patients who have undergone gastrectomies for early gastric cancer. Duodeno-gastric reflux, insufficient blood flow and denervation due to gastrectomies may promote carcinogenesis in remnant stomachs. It is important for physicians to recognize that the mucosa in remnant stomachs are at high risk of cancer, because they may already be in the stage of "initiation" of stomach carcinogenesis. When surgeons treat patients who suffer from stomach cancer, it may be reasonable for them to select reconstruction method which has less risk of producing remnant stomach cancer. The most important point for better prognoses for remnant stomach cancer is that patients be given clear directions to help them understand the risks related to remnant stomach cancer and the usefulness of regular health checkups. Having periodic physical checkups may help achieve earlier diagnoses and treatment. This will result in better prognoses for patients with remnant stomach cancer.
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