| Theme | Re-thinking Chromoendoscopy | |
|---|---|---|
| Title | Comparative Study of Magnifying Chromoendoscopy and Narrow Band Imaging for Estimation of Invasion Depth in Early Colorectal Cancer | |
| Publish Date | 2009/09 | |
| Author | Taku Sakamoto | Endoscopy Division, National Cancer Center Hospital |
| Author | Yutaka Saito | Endoscopy Division, National Cancer Center Hospital |
| Author | Takahisa Matsuda | Endoscopy Division, National Cancer Center Hospital |
| Author | Takeshi Nakajima | Endoscopy Division, National Cancer Center Hospital |
| Author | Shusei Fukunaga | Endoscopy Division, National Cancer Center Hospital |
| Author | Hirokazu Taniguchi | Pathology of Clinical Laboratory Division, National Cancer Center Hospital |
| [ Summary ] | Magnifying chromoendoscopy has been widely demonstrated in terms of its effectiveness in differentiating between colorectal neoplastic and non-neoplastic lesions. In addition it has also been employed to determine invasion depth of early colorectal carcinoma. The usefulness of the Narrow Band Imaging (NBI) systems for determining differentiation between colorectal neoplastic and non-neoplastic lesions, and for estimating invasion depth has also been demonstrated in some reports. However, there have been few reports comparing the usefulness of NBI or chromoendoscopy in determining the depth of early carcinomial invasion. In this study, we evaluate an NBI system for estimating invasion depth of early colorectal cancer. Agreements between colonoscopic, and chromoendoscopic examinations are discussed. The result suggest that the overall performance in estimating the depth of colorectal neoplasm invasion using the NBI system is equal to that for pit pattern analysis. However, there is more variability between observers using NBI than with pit pattern analysis (Kappa value 0.67 vs 0.41) in terms of analyzing the depth of invasion. Therefore, based on the above findings, priority should be given to pit pattern analysis to estimate invasion depth at this time. | |