Clinical Gastroenterology Vol.24 No.1(4-1)

Theme Consensus Terminology in Endoscopic Imaging -- Focusing on Image-enhanced Endoscopy
Title Endo-cytoscopy System
Publish Date 2009/01
Author Youichi Kumagai Department of Surgery, Ohta Nishinouchi Hospital
Author Kenrou Kawada Department of Surgery, Tokyo Medical and Dental University
Author Shigeru Yamazaki Department of Surgery, Ohta Nishinouchi Hospital
Author Yutaka Tohkairin Department of Surgery, Ohta Nishinouchi Hospital
Author Michio Iida Department of Surgery, Ohta Nishinouchi Hospital
Author Tatsuyuki Kawano Department of Surgery, Tokyo Medical and Dental University
[ Summary ] Recent advances of the technology enable us to observe more detailed information during endoscopic procedure. Diagnosis of the pit pattern or micro-vascular architecture allowed us the earlier detection of the neoplastic lesion in the gastrointestinal tract. These advances have led to the enhanced selection of appropriate treatments. Cancers that are discovered at an early stage can be treated with mucosal resection, whereas advanced cancers are treated with surgery.
Recently, some groups have tried to acquire a direct image of histology in vivo gastrointestinal mucosa (virtual histology or optical biopsy). To realize this conception, we developed the Endo-cytoscopy system that allows us up to 1,100 times magnifying observation in vivo. This instrument is "optical microscope" that can be inserted in the digestive tract. For magnified observation, vital staining, such as methylene blue or toluidine blue, is necessary to visualize the cells. Some investigators have been able to use this Endo-cytoscope to enhance cancer detection, and reported the usefulness of this technique.
This article is aimed to introduce the detail of this Endo-cytoscopy system and to assess the strengths and weaknesses of this technology with reference to the previously published articles.
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