| Theme | Nutrition Therapy for Liver Diseases | |
|---|---|---|
| Title | Triglyceride Homeostasis in Liver | |
| Publish Date | 2008/06 | |
| Author | Toshifumi Aoyama | Department of Metabolic Regulation, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine |
| Author | Naoki Tanaka | Department of Metabolic Regulation, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine |
| [ Summary ] | Recently, triglyceride accumulations in the liver have come to be considered capable of causing hepatic diseases such as hepatocellular carcinoma through HCV infection, ASH, NASH and other conditions. To understand the molecular mechanisms associated with hepatic triglyceride accumulation it is important to develop therapeutic and preventive treatments. The functions of and expressional regulation of important proteins directly involving in triglyceride homeostasis, as well as roles and characteristics of major nuclear proteins controlling the above mentioned proteins are discussed. | |