| Theme | Current Status of Colorectal Cancer Screening | |
|---|---|---|
| Title | Screening Colonoscopy Using Narrow Band Imaging (NBI) System | |
| Publish Date | 2008/02 | |
| Author | Masanori Toyoda | Department of Gastrointestinal Center, Sano Hospital |
| Author | Masahito Kotaka | Department of Gastrointestinal Center, Sano Hospital |
| Author | Mayumi Yamaguchi | Department of Gastrointestinal Center, Sano Hospital |
| Author | Asaka Tsuji | Department of Gastrointestinal Center, Sano Hospital |
| Author | Yasushi Sano | Department of Gastrointestinal Center, Sano Hospital / Department of GI Oncology & Endoscopy, National Cancer Center Hospital East |
| [ Summary ] | Narrow band imaging (NBI) systems are based on modifying spectral features by narrowing the bandwidth of spectral transmittance with optical filters. Since 1999, our team has been developing a proprietary NBI system. NBI modification provides unique images, emphasizing capillary pattern, and surface structures without dye solutions. NBI colonoscopy, focusing on magnifying observation of the microvascular architecture of colorectal lesions are reviewed. The utility of detailed observations of the microvascular architecture for differential diagnosis during NBI colonoscopy are also examined. Angiogenesis is critical for the transition of premalignant lesions to a hyperproliferative state to malignant phenotypes. Therefore, diagnosis based on angiogenic or vascular morphologic changes, may be ideal for early detection or diagnosis of neoplasms. In this review, the term “meshed capillary (MC) -like vessel” is proposed to make a distinction between non-neoplastic and neoplastic lesions, as well as the microvascular classification “capillary pattern CP”. This would be used for the differential diagnosis of colorectal lesions. It is believed that the combined use of NBI optical chromoendoscopy and real chromoendoscopy decreases the time and cost of screening colonoscopy. To assess the feasibility and efficacy of using NBI systems, further studies are required concerning colorectal lesions. |
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