| Theme | A Trend in the Practice of Pancreatitis | |
|---|---|---|
| Title | Autoimmune Pancreatitis and Extra-pancreatic Lesions-the Pathogenesis and Disease Concept | |
| Publish Date | 2008/09 | |
| Author | Hideaki Hamano | Department of Gastroenterology, Shinshu University School of Medicine |
| Author | Norikazu Arakura | Department of Gastroenterology, Shinshu University School of Medicine |
| Author | Mari Takayama | Department of Gastroenterology, Shinshu University School of Medicine |
| Author | Takeshi Uehara | Department of Laboratory Medicine, Shinshu University School of Medicine |
| Author | Shigeyuki Kawa | Center for Health, Safety and Environmental Management, Shinshu University |
| Author | Eiji Tanaka | Department of Gastroenterology, Shinshu University School of Medicine |
| [ Summary ] | Autoimmune pancreatitis (AIP) is a unique form of chronic pancreatitis characterized by high serum IgG4 concentrations and histological features such as those observed with lymphoplasmacytic sclerosing pancreatitis (LPSP) and abundant IgG4-bearing plasma cell infiltration. AIP has been reported to be associated with a variety of extra-pancreatic lesions including lachrymal and salivary glands, bile duct, pulmonary hilar lymph nodes, retroperitoneal lesions and prostate. Therefore, AIP should be recognized as a systemic inflammatory disease. | |