| Theme | Therapeutic Strategy for Early Gastrointestinal Cancers with EMR or ESD | |
|---|---|---|
| Title | Selecting Endoscopic Resection Method Based on Diameter of Squamous Cell Carcinoma | |
| Publish Date | 2008/01 | |
| Author | Ryu Ishihara | Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases |
| Author | Hiroyasu Iishi | Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases |
| Author | Yoji Takeuchi | Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases |
| Author | Koji Higashino | Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases |
| Author | Noriya Uedo | Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases |
| Author | Masaharu Tatsuta | Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases |
| [ Summary ] | Endoscopic mucosal resection (EMR) was developed as a less invasive treatment for superficial esophageal carcinoma. Resection of large lesions with EMR increases the risk of local recurrence at the resection site. Endoscopic submucosal dissection (ESD) has recently been developed for en bloc resection of large lesions. From January 2004 to April 2006, we treated 109 esophageal cancers based on our treatment strategies. Sixty-three lesions, less than 20 mm in diameter, were resected with EMR and 46 lesions, 20 mm or more in diameter with a pre-operative diagnostic depth deeper than mascularis mucosa, were resected by endoscopic submucosal dissection (ESD). No local recurrence occured. Seven post-operative strictures and one perforation in ESD group were observed. Treating small lesions, less than 20 mm in diameter, with EMR and large lesions with ESD would reduce local recurrence after endoscopic resection. | |