| Theme | Digestive Diseases Related to Bacteria -- To Understand Etiology and Control of Clinicopathological Conditions | |
|---|---|---|
| Title | Ano-Rectal Lesions with Inflammatory Bowel Disease and Infection | |
| Publish Date | 2007/08 | |
| Author | Kouhei Fukushima | Department of Surgery, Division of Biological Regulation and Oncology, Tohoku University Graduate School of Medicine |
| Author | Yuji Funayama | Department of Surgery, Division of Biological Regulation and Oncology, Tohoku University Graduate School of Medicine |
| Author | Hitoshi Ogawa | Department of Surgery, Division of Biological Regulation and Oncology, Tohoku University Graduate School of Medicine |
| Author | Iwao Sasaki | Department of Surgery, Division of Biological Regulation and Oncology, Tohoku University Graduate School of Medicine |
| Author | Kenichi Takahashi | Department of Surgery, Tohoku Rosai Hospital |
| [ Summary ] | Anal lesions associated with Crohn's disease are frequently observed and include anal fistula, perianal abscesses, recto-vaginal or urethral fistula, anal ulcers, skin tags, anal strictures, and cancer. Anal fistula is the most common condition observed and is treated with antibiotics, immunosuppressants, and / or anti-TNFα antibodies. Alternatively, surgical therapies, such as indwelling seton, ileo-or colo-stomy, or rectal amputation are required. Pouchitis is a non-specific mucosal inflammation developing in the pouch after surgery for ulcerative colitis. Endoscopy is important for diagnosis. The diagnostic criteria for these condition were established by members of the IBD research group in the Ministry of Health, Labour and Welfare. Proper medications and therapeutic guidelines have been proposed by the IBD research group. | |