Clinical Gastroenterology Vol.22 No.8(5-1)

Theme Clinical Application of Sentinel Node Concept for Carcinoma of the Alimentary Tract
Title Clinical Application of Sentinel Node Biopsy for EMR or ESD
Publish Date 2007/07
Author Shoji Natsugoe Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
Author Yoshikazu Uenosono Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
Author Takaaki Arigami Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
Author Yasushi Higashi Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
Author Takeo Arima Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
Author Katsuhiko Ehi Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
Author Tsutomu Kozono Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
Author Shigehiro Yanagita Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
Author Yawara Funasako Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
Author Takashi Aiko Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School of Medical and Dental Science
[ Summary ] Endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) is a useful treatment from the viewpoint of preserving organs and their functionality. Lymph node metastasis is the most important factor in early gastrointestinal cancer, when deciding on EMR or ESD. The presence of lymph node micrometastasis can be determined by biological and molecular methods, in addition to overt metastasis detected by imaging means. Recently, the sentinel lymph node concept has been introduced for treatment of early gastrointestinal cancer. It is useful to provide less invasive treatment by examining lymph node micrometastasis after identification of sentinel node. In the near future, extension of indications for EMR or ESD may be established through the use of sentinel node biopsy based on the diagnosis of lymph node micrometastasis.
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