| Theme | Clinical Application of Sentinel Node Concept for Carcinoma of the Alimentary Tract | |
|---|---|---|
| Title | Sentinel Lymph Node Theory for Colorectal Cancer and Clinical Application | |
| Publish Date | 2007/07 | |
| Author | Kimihiko Funahashi | Division of Gastroenterological Surgery, Omori Hospital, Toho University Medical Center |
| Author | Junichi Koike | Division of Gastroenterological Surgery, Omori Hospital, Toho University Medical Center |
| Author | Naoyasu Saito | Division of Gastroenterological Surgery, Omori Hospital, Toho University Medical Center |
| Author | Satomoto Kurihara | Division of Gastroenterological Surgery, Omori Hospital, Toho University Medical Center |
| Author | Hiroyuki Shiokawa | Division of Gastroenterological Surgery, Omori Hospital, Toho University Medical Center |
| Author | Mitsunori Ushigome | Division of Gastroenterological Surgery, Omori Hospital, Toho University Medical Center |
| Author | Kentaro Shirasaka | Division of Gastroenterological Surgery, Omori Hospital, Toho University Medical Center |
| Author | Tomohiko Goto | Division of Gastroenterological Surgery, Omori Hospital, Toho University Medical Center |
| Author | Tatsuo Teramoto | Division of Gastroenterological Surgery, Omori Hospital, Toho University Medical Center |
| [ Summary ] | Identification of SLNs in connection with colorectal cancer has many benefits from the point of expanding indications for laparoscopic surgery for advanced cancer and avoiding postoperative disturbance of rectal or anal cancer. The results from our department using dye or radioisotope suggested that in identifying SLNs, there were limitations in identifying lymph nodes to which tumor cells had metastasized massively or diffusely. However, the lymph nodes that were identified as SLN, had a high rate of metastatic lymph nodes present. It was possible to identify true regional lymph nodes that drain directly from the tumor (draining lymph node basin : DLB) through SLN mapping. However, there are still many uncertainties in applying SLN theory to colorectal cancer in relation to the postoperative advantages and the risks of decreasing cure rates for tumors. |
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