| Theme | Clinical Application of Sentinel Node Concept for Carcinoma of the Alimentary Tract | |
|---|---|---|
| Title | Detection of Sentinel Node -- Dye-directed Method | |
| Publish Date | 2007/07 | |
| Author | Takashi Fujimura | Gastroenterologic Surgery, Kanazawa University |
| Author | Shinichi Kinami | Gastroenterologic Surgery, Kanazawa University |
| Author | Sachio Fushida | Gastroenterologic Surgery, Kanazawa University |
| Author | Masato Kayahara | Gastroenterologic Surgery, Kanazawa University |
| Author | Tetsuo Ohta | Gastroenterologic Surgery, Kanazawa University |
| Author | Koichi Miwa | Toyama Rosai Hospital |
| [ Summary ] | Dyes, such as Lymphazurin, patent blue V, and indocyanine green, are frequently used as tracers for sentinel node mapping. This is because dye-directed mapping is less expensive and does not require any special equipment other than that used with the radioisotope-guided method. Stained lymph nodes and lymphatics can be observed with the naked eye. However, the performance of the dye-directed mapping requires training to learn how to inject dye and how to search for stained lymph nodes, requiring experience with at least 30 patients. Sentinel node mapping, using these dyes, is applied for gastric and colonic cancer in the gastrointestinal field. Identification and accuracy rates are over 90 % and over 85 %, respectively. To improve outcomes in the dye-directed mapping it is necessary to utilize some devices to detect indocyanine green staining and to develop new fluorescein dyes. |
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