| Theme | Gastrointestinal Disease in the Elderly Focusing on Minimally Invasive Therapy | |
|---|---|---|
| Title | Risk Factors for Rebleeding and Thirty-day Mortality after Endoscopic Hemostasis in Elderly Bleeding Peptic Ulcer Patients | |
| Publish Date | 2007/12 | |
| Author | Kei Aoki | The Third Department of Internal Medicine, Kyorin University School of Medicine |
| Author | Yasuharu Yamaguchi | The Third Department of Internal Medicine, Kyorin University School of Medicine |
| Author | Shin-ichi Takahashi | The Third Department of Internal Medicine, Kyorin University School of Medicine |
| [ Summary ] | A total of 200 patients aged 70 years or older underwent endoscopic hemostasis for bleeding peptic ulcers between January 1994 and December 2005. The clinical variables and endoscopic characteristics of their ulcers are compared in relation to those patients who did or did not have rebleeding and 30-day mortality rates. Multivariate analysis was performed using a logistic regression model expressed as an odds ratio in a 95 % confidence interval. Among the 200 patients in this study, the rebleeding rate was 15. 5 % (31 cases), and the 30-day mortality rate was 7.5 % (15 cases of which the cause of death was peptic ulcers in only one case). The results showed that the presence of shock (2.4 ; 1.0 - 6.0, p < 0.05), volume of transfusion over 6 units within 24 hours (11.42 ; 3.56 - 36.61, p < 0.05) and ulcer size over 3 cm (3.2 ; 1.2 - 8.7, p < 0.05) were significant risk factors for rebleeding. In relation to 30-day mortality rates, patients with concomitant disease (7.8 ; 1.0 - 60.4, p < 0.05) and those who were inpatients (31.5 ; 8.2 - 121.4, p < 0.01) were at significant risk. | |