| Theme | Guidebook of Pathology for Gastroenterologists and Hepatologists ; Including Special Stains and Immunohistochemistry | |
|---|---|---|
| Title | Pathological Diagnosis of Mesenchymal Tumors of the Digestive System | |
| Publish Date | 2007/09 | |
| Author | Mayumi Shincho | Department of Surgical Pathology, Hyogo College of Medicine |
| Author | Ikuo Matsuda | Department of Surgical Pathology, Hyogo College of Medicine |
| Author | Seiichi Hirota | Department of Surgical Pathology, Hyogo College of Medicine |
| [ Summary ] | Mesenchymal tumors of the digestive system are often found incidentally through endoscopy or ultrasonography. Gastrointestinal stromal tumors (GISTs) are those most commonly found. Molecular target therapy, using imatinib, is effective for patients with metastatic or unresectable GISTs. Therefore, accurate diagnosis for GISTs is essential. Immonohistochemical staining, using appropriate antibodies including KIT, is required for differential diagnosis of gastrointestinal mesenchymal tumors. | |