Clinical Gastroenterology Vol.21 No.6(6)

Theme Preventive Medicine of Gastrointestinal Cancer
Title Secondary Prevention of Gastric Cancer : Present and Future
Publish Date 2006/06
Author Junichi Okuda Department of Internal Medicine, Murakami Memorial Hospital, Asahi University
Author Kazunori Ida Department of Internal Medicine, Murakami Memorial Hospital, Asahi University
Author Hiromi Sakai Department of Internal Medicine, Murakami Memorial Hospital, Asahi University
Author Chihiro Yokomizo Department of Internal Medicine, Murakami Memorial Hospital, Asahi University
Author Takao Kojima Department of Internal Medicine, Murakami Memorial Hospital, Asahi University
Author Takahiro Kato Department of Internal Medicine, Murakami Memorial Hospital, Asahi University
[ Summary ] The number of people who underwent mass screening for gastric cancer in 2003 was 5,975,956. Gastric cancer was discovered in 5,970 people, with a detection rate of 0.099 %. The breakdown of gastric cancer sizes was as follows : ≤1 cm, 15.9 % ; 1.1 - 2.0 cm, 25.2 % ; 2.1 - 3.0 cm, 18.8 % ; and ≤3.1 cm, 40.1 %. Invasion depths for gastric cancer were as follows : M 42.3 % ; and SM 27.3 %. Early cancer thus accounted for 69.5 % of the total, and 54.4 % of Type 0 were IIc.
A new X-ray technique has been developed to improve gastric mucosa visualization and early gastric cancer detection as well as to lower the percentage of people requiring additional tests. With this new technique, a small amount (131 - 150 ml) of highly-concentrated, low-viscosity contarast media (200 - 220 W / V %) is used. Different imaging techiniques, primarily double-contrast radiography, are combined with the above mentioned modalities.
In recent years, to efficiently diagnose gastric cancer, identify early gastric cancer and establish cancer screening in which endoscopic therapy is possible, studies have been conducted to combine pepsinogen and Helicobacter pylori tests. Furthermore, studies have been conducted to review endoscopic screening and identify individuals at high risk of cancer.
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