| Theme | Update on Hepatitis E | |
|---|---|---|
| Title | Hepatitis E Virus Genome Database | |
| Publish Date | 2006/05 | |
| Author | Tadasu Shin-i | Department of Clinical Molecular Informative Medicine, Nagoya City University Graduate School of Medical Sciences |
| Author | Masashi Mizokami | Department of Clinical Molecular Informative Medicine, Nagoya City University Graduate School of Medical Sciences |
| [ Summary ] | Over 1,000 Hepatitis E Virus (HEV) sequences are now publicly available, and the number of these sequences is increasing rapidly. Therefore, it is worthwhile to construct a specialized database for viral sequences and to make it accessible to researchers worldwide. We have developed a database known as the “Hepatitis Virus Database (HVDB)”, which contains all the HCV and HBV sequences publicly available, and now we have made an HEV data set in the HVDB and opened it to the public. In the HVDB, all piece sequences obtained from public databases are arranged in relation to the genome sequence of HEV. Also, given in the database, are the phylogenetic relationships of each locus on the genome, including variants. Therefore, users can easily retrieve entries for specific genome types by referring to the phylogenetic relationships or those of specific loci by referring to the genome map information. The HVDB also provides users with a tool for phylogenetic analysis that can be used in combination with data retrieval tools. The HVDB is valuable not only for academic purposes, such as phylogenetic analyses, but also for clinical purposes, such as diagnoses and vaccine development. The database is publicly accessible through the following URL : http //s2asO2.genes.nig.ac.jp |
|