| Theme | Current Status of Magnifying Endoscopy | |
|---|---|---|
| Title | Diagnosis of Early Gastric Cancer with Magnifying Endoscopy, Emphasizing Use of Magnifying Narrow Band Imaging | |
| Publish Date | 2006/04 | |
| Author | Junko Fujisaki | Division of Endoscopy, The Cancer Institute Ariake Hospital, Japan Foundation for Cancer Research |
| Author | Akiyoshi Ishiyama | Division of Endoscopy, The Cancer Institute Ariake Hospital, Japan Foundation for Cancer Research |
| Author | Mitsuo Saito | Division of Endoscopy, The Cancer Institute Ariake Hospital, Japan Foundation for Cancer Research |
| Author | Hiroshi Takahashi | Division of Endoscopy, The Cancer Institute Ariake Hospital, Japan Foundation for Cancer Research |
| Author | Etsuo Hoshino | Division of Endoscopy, The Cancer Institute Ariake Hospital, Japan Foundation for Cancer Research |
| Author | Yo Kato | Division of Pathology, The Cancer Institute Ariake Hospital, Japan Foundation for Cancer Research |
| [ Summary ] | Narrow Band Imaging (NBI) is a newly developed device, which produces information on the microvascular structures of the GI mucosa. One aim of this study is to investigate the usefulness of magnified NBI for more accurate endoscopic diagnosis of early gastric cancer. The structures of magnified NBI were classified as follows ; fine-network, oval, spiral, and irregular patterns. Well differentiated adenocarcinomas typically showed fine network patterns. Moderately differentiated adenocarcinomas typically showed oval or spiral patterns. Poorly differentiated adenocarcinomas typically showed irregular patterns. The margin of the cancer was more clearly defined in cases of depressed type (“IIc”) early gastric cancer. We evaluated information about gastric adenoma as diagnosed with biopsy. 44 out of 62 cases showed a fine network, with oval and irregular vascular pattens. 37 (84%) cases were diagnosed as cancer in cases of adenoma or well differentiated adenocarcinoma after EMR or ESD. Magnified NBI observation was useful for pretreatment and histological evaluation of early gastric cancer and for accurate demarcation of the margins of depressed type (IIc) early gastric cancers. |
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