| Theme | Diagnostic Strategy of Pancreatic Carcinoma in Early Stage | |
|---|---|---|
| Title | Small Pancreatic Carcinoma : from Surgical Pathology | |
| Publish Date | 2006/12 | |
| Author | Koji Yamaguchi | Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University |
| Author | Hiroki Tohma | Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University |
| Author | Shunichi Takahata | Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University |
| Author | Norihiro Sato | Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University |
| Author | Masafumi Nakamura | Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University |
| Author | Masazumi Tsuneyoshi | Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University |
| Author | Masao Tanaka | Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University |
| [ Summary ] | Despite recent progresses in diagnostic modalities and therapeutic procedures, pancreatic cancer is usually detected in the advanced stages and the clinical course remains dismal. However, if pancreatic cancer is diagnosed at an early stage and adequate surgery followed by effective adjuvant therapy is done, the clinical course may be favorable. Further examination of the pancreas in cases of IPMN, onset of diabetes mellitus in elderly patients and deterioration associated with diabetes mellitus may provide diagnostic clues for the detection of early, small pancreatic cancer. For patients with pTS 1 pancreatic cancer, R 0 operations with D 2 lymph node dissection are indicated and follow up adjuvant therapy, such as the use of gemicitabine, is important. | |