Clinical Gastroenterology Vol.21 No.12(2)

Theme Non-B, Non-C Hepatitis
Title Chronic Non-B, Non-C Hepatitis and Hepatitis Viruses
Publish Date 2006/11
Author Eiji Tanaka Department of Medicine, Shinshu University School of Medicine
Author Takeji Umemura Department of Medicine, Shinshu University School of Medicine
Author Kendo Kiyosawa Department of Medicine, Shinshu University School of Medicine
[ Summary ] Patients with chronic hepatitis exist who are negative for hepatitis B and C viral markers. Such patients are diagnosed as having non-B, non-C chronic hepatitis. Recently, GB virus C (GBV-C), hepatitis G virus (HGV), TT virus (TTV), and SEN virus (SENV) have been suspected of being candidates for non-B, non-C hepatitis viruses. Virological analyses have shown that GBV-C and HGV are the same viruses. GBV-C / HGV can be transmited through blood transfusions and results in persistent infections. However, no evidence has been found that the virus causes hepatitis. TTV and SENV are categorized in a similar viral group. Genotype 1 TTV and genotypes G, as well as H SENV have been analyzed to determine if they are hepatitis viruses or not. As a result, none of them are considered to be new hepatitis virus at this time.
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