| Theme | GIST (gastrointestinal stromal tumor) | |
|---|---|---|
| Title | Endoscopic Diagnosis of GIST : Small and Large Intestine | |
| Publish Date | 2005/08 | |
| Author | Masahiro Yamada | Division of Therapeutic Therapy, Department of Internal Medicine, Nagoya Graduate School of Medicine |
| Author | Yasumasa Niwa | Division of Therapeutic Therapy, Department of Internal Medicine, Nagoya Graduate School of Medicine |
| Author | Naoki Ohmiya | Division of Therapeutic Therapy, Department of Internal Medicine, Nagoya Graduate School of Medicine |
| Author | Hidemi Goto | Division of Therapeutic Therapy, Department of Internal Medicine, Nagoya Graduate School of Medicine |
| [ Summary ] | Small intestinal and large intestinal GISTs are comparatively rare diseases. Endoscopic findings of these GISTs are the same as those of gastric GISTs. The tumor is covered by normal mucosa and has the configuration of submucosal tumors with bridging folds and, also the accompanying findings of erosion and ulcers. EUS has recently been reported to be useful in the diagnosis of submucosal tumors. In EUS findings, GIST originates in the fourth sonographic layer of the GI tract wall and is often accompanied with irregular borders or cystic spaces. However, there are some cases in which the EUS diagnosis is questionable. In such cases, ensdoscopic ultrasound guided fine needle aspiration (EUS-FNA) is a useful technique for histological diagnosis. With the increased use of double balloon enteroscopy and capsular enteroscopy, it seems that more small intestinal GISTs will be diagnosed preoperatively in the future. | |