Clinical Gastroenterology Vol.20 No.2(7)

Theme How to Manage Distant Metastases from Gastrointestinal Cancer?
Title Stereotactic Radiotherapy for Lung Metastases from Colorectal Cancer
Publish Date 2005/02
Author Minoru Uematsu Department of Radiation Oncology, Keio University School of Medicine
[ Summary ] Stereotactic radiotherapy (SRT) is highly effective for treatment of small lung cancer. We reviewed the treatment results from 20 patients with 42 lung metastases from colorectal cancer. Between 1994 and 2000, we treated 20 patients with SRT dosages of 50-60 Gy per 4-5 fractions over a one week per old, using a fusion of the CT and linac (FOCAL) units. After SRT, all 42 lesions should marked regression in size and only 4 lesions in 2 patients (10 %) showed local failures on follow-up CT scans. Overall survival rates following SRT, were 86 % at 12 months, 63 % at 24 months, and 18 % at 36 months. No patients died of local failures of the irradiated sites, and all the causes of death were systemic failures. No remarkable adverse effects were observed after SRT. SRT for metastatic lung cancers from colorectal cancers was safe and effective for local control.
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