| Theme | Debatable Issues in Living-Donor Liver Transplantation | |
|---|---|---|
| Title | Living Donor Liver Transplantation in Patients with Human Immunodeficiency Virus / Hepatitis C Viral Co-Infection | |
| Publish Date | 2005/11 | |
| Author | Yasuhiko Sugawara | Departments of Artificial Organ & Transplantation Surgery, Graduate School of Medicine, University of Tokyo |
| Author | Masatoshi Makuuchi | Departments of Artificial Organ & Transplantation Surgery, Graduate School of Medicine, University of Tokyo |
| Author | Kunihisa Tsukada | Infectious Diseases (Internal Medicine), Graduate School of Medicine, University of Tokyo |
| Author | Kazuhiko Koike | Infectious Diseases (Internal Medicine), Graduate School of Medicine, University of Tokyo |
| [ Summary ] | Highly active anti-retroviral therapy (HAART) for the human immunodeficiency virus (HIV) has delayed disease progression. The advances prompted us to undertake living donor liver transplantation in 6 hemophilia patients coinfected with HIV and hepatitis C virus (HCV). Four of the 6 patients survived living donor liver transplantation with the observation time ranging from 8 to 50 months. Utilizing an organ from living relatives should be one of the options to help resolve the concerns around the utilization of scarce public sources from cadavers. These patients may not have survival rates equivalent HIV negative patients. | |