Clinical Gastroenterology Vol.20 No.11(15)

Theme Present Status and Future Aspects of EUS
Title Current Status and Future Direction of Interventional EUS in the United States
Publish Date 2005/10
Author Norio Fukami Department of Gastrointestinal Medicine and Nutrition, The University of Texas M.D. Anderson Cancer Center
[ Summary ] Endoscopic ultrasonography emerged as an innovative imaging modality years ago. Its capabilities were expanded with the invention of curvilinear array echoendoscope, which has the ability for tissue acquisition with fine-needle aspiration (EUS-FNA). The indications for the EUS-FNA are rapidly expanding from submucosal tumors, pancreatobiliary neoplasms and surrounding lymph nodes to a wide variety of adjacent organs and tumors outside the gastrointestinal tract. The complications of EUS-FNA were reviewed and the complication rate was considered to be similar to that with other imaging guided FNA. Currently, EUS-FNA is the preferred method for tissue acquisition from pancreas tumors in the U.S.
EUS-guided cholangiopancreatography with subsequent internal drainage has been described in cases with failed endoscopic retrograde cholangiopancreatography and in some cases with challenging anatomy.
Applying the same technique of FNA, innovative drug delivery with fine needle injection (FNI) has been studied. EUS-FNI is an attractive technique to deliver various therapeutic agents directly into approachable tissues and tumors. Ongoing clinical and translational researches will assist making further progress in the clinical use of EUS-FNA and FNI.
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