| Theme | Helicobacter pylori update | |
|---|---|---|
| Title | Various Problems After Eradication of Helicobacter pylori | |
| Publish Date | 2005/01 | |
| Author | Tomoari Kamada | Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| Author | Kuniaki Sugiu | Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| Author | Aki Muranaka | Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| Author | Hiroaki Kusunoki | Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| Author | Jiro Hata | Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School |
| Author | Ken Haruma | Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| [ Summary ] | Recently, various problems after eradication of Helicobacter pylori (H. pylori) have been reported, such as the development of reflux esophagitis, increases in clarithromycin resistance to H. pylori, and the occurrence of gastric cancer and obesity. The presence of hiatal hernias and corpus gastritis are closely related to the development of reflux esophagitis after eradication of H. pylori. Therefore, full informed consent by patients is needed before eradication of H. pylori. Because it is rare for reflux esophagitis, which develops after eradication of H. pylori, to become severe and cause longterm reflux symptoms, it rarely becomes a longterm clinical problem among patients who complete therapy successfully. Further study needs to be done on the development of Barrett's mucosa, which may be a cause of esophageal adenocarcinoma. |
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