| Theme | Infectious Enterocolitis | |
|---|---|---|
| Title | Antibiotic Associated Enterocolitis | |
| Publish Date | 2004/07 | |
| Author | Shinichi Katsuki | Center for Gastroenterology, Keiwakai Tokeidai Hospital |
| Author | Hisato Homma | Center for Gastroenterology, Keiwakai Tokeidai Hospital |
| Author | Takehide Akiyama | The Fourth Department of Internal Medicine, Sapporo Medical University |
| Author | Ken Murakami | The Fourth Department of Internal Medicine, Sapporo Medical University |
| Author | Shinichi Mezawa | Center for Gastroenterology, Keiwakai Tokeidai Hospital |
| Author | Tetsuji Takayama | The Fourth Department of Internal Medicine, Sapporo Medical University |
| [ Summary ] | Antibiotic associated diarrhea is a common symptom for the majority of clinicians. We can classify enterocolitis into three types; acute hemorrhagic colitis, pseudomembranous colitis and MRSA enteritis. Acute hemorrhagic colitis is mainly caused by oral usage of penicillin and its derivatives. The cause of this disease is still unknown but it is suggested that allergic reactions, ischemic changes or overgrowth of Klebsiella oxytoca and Clostridium difficile toxin may be linked. Pseudomembranous colitis is commonly detected in older people and patients having malignant or blood related diseases who have been given antibiotics. This disease is caused by Clostridium difficile toxin A and B. MRSA enteritis has recently become a common disease and is seen as a nosocomial infection. Third generatinon cephalosporin administration and gastric acid inhibition are necessary to treat MRSA infections in the intestinal mucosa. | |