| Theme | Recent Advances in Diagnosis and Treatment of Reflux Esophagitis | |
|---|---|---|
| Title | Helicobacter pylori and Reflux Esophagitis | |
| Publish Date | 2004/11 | |
| Author | Ken Haruma | Division of Gastroenterology, Department of Intestinal Medicine, Kawasaki Medical School |
| Author | Tomoari Kamada | Division of Gastroenterology, Department of Intestinal Medicine, Kawasaki Medical School |
| Author | Keisuke Honda | Division of Gastroenterology, Department of Intestinal Medicine, Kawasaki Medical School |
| Author | Kuniaki Sugiu | Division of Gastroenterology, Department of Intestinal Medicine, Kawasaki Medical School |
| Author | Motonori Sato | Division of Gastroenterology, Department of Intestinal Medicine, Kawasaki Medical School |
| Author | Noriaki Manabe | Department of Endoscopy, Hiroshima University Hospital |
| [ Summary ] | Helicobacter pylori (H. pylori) is an important pathogen that is known to be associated with gastritis, peptic ulcer diseases, and gastric cancer. H. pylori infection plays a role in reflux esophagitis. However, this role is uncertain, as recent studies have indicated that patients in Japan with reflux esophagitis have a lower prevalence of H. pylori infections than patients from western Europe or North America and that H. pylori might help to protect against reflux esophagitis. The frequency of hypochlorhydria, due to atrophic gastritis, induced by H. pylori infection, is associated with the low prevalence of reflux esophagitis in Japan. | |