| Theme | Diagnosis and Treatment of Non-ulcer Dyspepsia | |
|---|---|---|
| Title | Motility Disorders and NUD (non-ulcer dyspepsia) | |
| Publish Date | 2003/04 | |
| Author | Hiroaki Kusunoki | Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| Author | Ken Haruma | Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| Author | Tomoari Kamada | Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| Author | Keisuke Honda | Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| Author | Jiro Hata | Department of Gastroenterology, Miyoshi General Hospital |
| Author | Noriaki Manabe | Department of Medicine and Molecular Science, Hiroshima University Graduate School of Biomedical Sciences |
| [ Summary ] | Although several pathophysiologic factors such as gastric acid, visceral sensation, gastrointestinal motility and psychosocial factors, such as stress, may play roles in the pathogenesis of non-ulcer dyspepsia (NUD), the exact pathogenesis of dyspepsia remains unknown. Gastrointestinal dysmotility has been reported as one of the major pathogenetic factors in patients with NUD. In previous studies, impaired fasting gastric motility, delayed gastric emptying, decreased antral contractions, gastric dysrhythumias, increased duodenogastric reflux and impaired accommodation of the proximal stomach were seen in about 30 to 50% of NUD patients. In this review, we describe details concerning motility disorders in patients with NUD. | |