Clinical Gastroenterology Vol.18 No.1(11)

Theme Life Style and Digestive Diseases
Title Microflora Targeted Therapies for Inflammatory Bowel Disease: Pro- and Prebiotics
Publish Date 2003/01
Author Keiichi Mitsuyama Second Department of Medicine, Kurume University School of Medicine
Author Satoshi Matsumoto Yakult Central Institute for Microbiological Research
[ Summary ] Although the causes of the inflammatory bowel disease remain incompletely understood, increasing evidence implicates intestinal microflora in the pathogenesis of these disorders. Modulation of the intestinal flora therefore may offer a plausible therapeutic approach. While recent data support a potential therapeutic role for probiotics, prebiotics and synbiotics, such treatments need to be further assessed by large scale studies. A better understanding of the intestinal microflora and the mechanisms of their action may help us to develop more effective treatments for inflammatory bowel disease.
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