| Theme | Lesions of Esophagogastric Junction -- Its Diagnostic and Therapeutic Strategies | |
|---|---|---|
| Title | Mallory-Weiss Syndrome | |
| Publish Date | 2002/04 | |
| Author | Satoshi Tanabe | Department of Internal Medicine, Kitasato University |
| Author | Norisuke Nakayama | Department of Internal Medicine, Kitasato University |
| Author | Toru Sasaki | Department of Internal Medicine, Kitasato University |
| Author | Katsuhiko Higuchi | Department of Internal Medicine, Kitasato University |
| Author | Wasaburo Koizumi | Department of Internal Medicine, Kitasato University |
| Author | Katsunori Saigenji | Department of Internal Medicine, Kitasato University |
| [ Summary ] | Mallory-Weiss syndrome is one of the causes of upper gastrointestinal hemorrhage, in which an abrupt rise in abdominal pressure, due to nausea or vomiting, induces a tear near the esophagogastric junction. Mallory-Weiss syndrome represents about 3-15% of all cases of upper gastrointestinal hemorrhage. Hemorrhage frequently ceases spontaneously. When endoscopic findings reveal persistent hemorrhage, endoscopic hemostatic techniques, using heater probe ther mocoagulation or hemoclipping, are necessary. Endoscopic ligation is also useful, especially for severe bleeding. In uncontrolled cases using endoscopic hemostasis, IVR or surgical operarions should be selected as means of treatment. After endoscopic hemostasis, fasting and inhibitors of acid secretion (H2-receptor antagonists or proton pump inhibitors) are recommended. | |