Clinical Gastroenterology Vol.16 No.5(3)

Theme Chemotherapy for Gastrointestinal Malignancy
Title Chemotherapy for Advanced Gastric Cancer
Publish Date 2001/05
Author Wasaburo Koizumi Department of Internal Medicine I, Kitasato University, School of Medicine
Author Satoshi Tanabe Department of Internal Medicine I, Kitasato University, School of Medicine
Author Shizuka Nagaba Department of Internal Medicine I, Kitasato University, School of Medicine
Author Katsuhiko Higuchi Department of Internal Medicine I, Kitasato University, School of Medicine
Author Satoshi Murakami Department of Internal Medicine I, Kitasato University, School of Medicine
Author Katsunori Saigenji Department of Internal Medicine I, Kitasato University, School of Medicine
[ Summary ] In Japan, gastric cancer remains a leading cause of death, due to malignant neoplasms. In cases of advanced and recurent gastric cancer it is difficult to perform curative resection. Chemotherapy for advanced gastric cancer is still seen as the main supporting therapy. However, recently some new anti cancer agents have been undergoing clinical trials and have demonstrated potential activity in patients. It has been reported in some papers, that TS-1 or Irinotecan hydrochloride (CPT-11) are effective. A combination of the therapies is expected to provide a new theraputic approarch.
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