Clinical Gastroenterology Vol.16 No.5(11)

Theme Chemotherapy for Gastrointestinal Malignancy
Title Tumor Dormancy by Anti-Angiogenesis
Publish Date 2001/05
Author Yutaka Takahashi Department of Surgical Oncology, Cancer Research Institute, Kanazawa University
Author Masayoshi Mai Department of Surgical Oncology, Cancer Research Institute, Kanazawa University
[ Summary ] Clinical trials of anti-angiogenetic drugs, such as anti vascular endothelial cell growth factor (VEGF) antibody, inhibitor of VEGF receptor tyrosine kinase, are in phase II/III studies in the United States and Europe. In this paper, we introduced data concerning these drugs in relation to colorectal cancer and discussed strategies related to anti-angiogenesis, not associated with tumor atrophy, but to tumor dormancy.
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