Clinical Gastroenterology Vol.16 No.13(1-5)

Theme Gastroenterological Diseases and Therapy with Transplantation
Title Long Term Complications after Liver Transplantation
Publish Date 2001/12
Author Hiroyuki Furukawa Organ Transplantation and Regenerative Medicine, Hokkaido University School of Medicine
Author Tsuyoshi Shimamura Gastroenterological Surgery and General Surgery, Hokkaido University School of Medicine
Author Maeng Bong Jin Organ Transplantation and Regenerative Medicine, Hokkaido University School of Medicine
Author Toshikana Kamiyama Gastroenterological Surgery and General Surgery, Hokkaido University School of Medicine
Author Michiaki Matsushita Gastroenterological Surgery and General Surgery, Hokkaido University School of Medicine
Author Satoru Todo Gastroenterological Surgery and General Surgery, Hokkaido University School of Medicine
[ Summary ] The outcome of liver transplantation, either using living or cadaver donors, has significantly improved. The five year survival rate has reached 75% to 80%. However, there still remain many problems to be solved. Although the short-term complications are well known, little is known about the long-term complications. Therefore, the long-term complications were presented in this chapter; 1) technical complications such as hepatic artery thrombosis, hepatic vein thrombosis, and biliary stricture, 2) immunologic complication such as chronic rejection, 3) adverse effects of immunosuppressive agents such as renal dysfunction, hypertension, diabetes, neurologic disorders, obesity, and hypercholesterolemia.
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