Theme | Endoscopic Diagnosis of Helicobater pylori Infection | |
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Title | Diagnosis of Helicobacter pylori Infection by Combined Endoscopic Methods | |
Publish Date | 2001/10 | |
Author | Kazunori Ida | Department of Internal Medicine, Murakami Memorial Hospital, Asahi University |
Author | Masaaki Kuroda | Department of Internal Medicine, Murakami Memorial Hospital, Asahi University |
Author | Hisato Tsuboi | Department of Internal Medicine, Murakami Memorial Hospital, Asahi University |
Author | Hiroo Hatakeyama | Department of Internal Medicine, Murakami Memorial Hospital, Asahi University |
Author | Naoyuki Matsumoto | Department of Internal Medicine, Murakami Memorial Hospital, Asahi University |
Author | Junichi Okuda | Department of Internal Medicine, Murakami Memorial Hospital, Asahi University |
[ Summary ] | Gastric mucosa affected with H.pylori (Hp) infection have a different appearance than Hp negative, normal mucosa, having diffuse redness, spotty redness in the fundic mucosa and swollen folds in the corpus. The results of endoscopic diagnosis of Hp infection, based on these 3 findings, were a sensitivity of 94% and a specificity of 81%. The same results, obtained by the application of Hemoglobin index (IHb) measurement, for which the cut off index was determined to be 60, were a sensitivity of 91% and a specificity of 95%. The results obtained by using the contrast method were 83% and 95% respectively. Subjects diagnosed as being suspect or negative for Hp infection, from above mentioned 3 characteristic findings of conventional endosocopy were rediagnosed, using results obtained with IHb measurement and the contrast method. The results for each diagnostic group rose slightly, but the substitution of other diagnostic methods created a more sure diagnosis. |