Clinical Gastroenterology Vol.16 No.11(3)

Theme Endoscopic Diagnosis of Helicobater pylori Infection
Title Changes of Endoscopic Findings of Gastric Mucosa After Eradication of Helicobacter pylori
Publish Date 2001/10
Author Nobuhiro Sakaki Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital
[ Summary ] After infection by H.pylori of normal gastric mucosa, infammatory change occurs first, and then atrophic change develops. On the other hand, superficial changes including reddening and erosion occur temporarily. In this paper, we will discuss preliminary data concerning changes in endoscopic findings for gastric mucosa after eradication of H.pylori, from the view point of endoscopic diagnosis of gastritis. The endoscopic inflammatory changes, which included not only giant folds and nodularity but also granular mucosa which was observed on the lesser curvature of the gastric body, and were reduced after eradication of H.pylori. In spite of recovering from histological atrophy, the endoscopic atrophic changes did not show any remarkable degree of change, in many cases, after eradication. Concerning endoscopic superficial change, erosion showed no relation to eradication. There is a great deal of controversial data concerning reddening, for which a diagnostic criteria has not been established.
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