| Theme | Direction of the Prescription for Gastrointestinal Tract | |
|---|---|---|
| Title | Mucosal Protective Agent | |
| Publish Date | 1998/12 | |
| Author | Takao Wakabayashi | Department of Internal Medicine, Second Teaching Hospital, Fujita Health University School of Medicine |
| Author | Saburo Nakazawa | Department of Internal Medicine, Second Teaching Hospital, Fujita Health University School of Medicine |
| [ Summary ] | In Japan, the patients with peptic ulcers have been treated with many kinds of drugs, known as mucosal protective agents, including acid inhibitor. Mucosal protective agents do not have a great effect on healing of ulcers. Therefore, many of them are usually administrated along with H2 receptor antagonists or proton pump inhibitors, in all but a few cases. Although it is thought that mucosal protective agents play some characteristic roles in the healing of ulcers, those detailed mechanism and clinical effects are not completely understood. The efficacy and administration of the drugs primarily used as mucosal protective agents were discussed in this chapter. | |