Clinical Gastroenterology Vol.13 No.12(10)

Theme Gastorointestinal Diseases --from the Standpoint of Psychosomatic Medicine
Title Depressive Patients Associated with Peptic Ulcer -- from the Standpoint of Syndrome Shift (Groen,J.J.)
Publish Date 1998/11
Author Michinori Nakayama Department of Psychiatry, National Defense Medical College
Author Michiya Doi Department of Psychiatry, National Defense Medical College
[ Summary ] The authors retrospectively investigated the clinical features of 15 depressive patients and their association with peptic ulcers. Depression begins either in the course of treatment or immediately after the healing of peptic ulcer. These cases are categorized as post-ulcerative depression, that is seen as one of the refractory or therapy-resistant subtypes of depression. Post-ulcerative depression often manifests itself as monopolar depression rather than the recurrent types of depression, such as bipolar or unipolar. Substitution of peptic ulcers for depression in these patients might be perceived as a sort of somatopsychic syndrome shift (Groen,J.J.), but it is more practical to see it merely as an association of the two syndromes, brought about partly due to certain iatrogenic factors.
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