| Theme | Pancreatic Endocrine Tumors | |
|---|---|---|
| Title | Differential Diagnosis, Syndromes and Imaging Diagnosis of Pancreatic Endocrinomas | |
| Publish Date | 1997/08 | |
| Author | Jun Soga | College of Biomedical Technology, Niigata University |
| [ Summary ] | A total of 1841 cases with pancreatic endocrinomas computerized in the Niigata Registry were analyzed from the viewpoints of preoperative diagnosis, differential diagnosis, syndromes, and imaging methods for detecting the locations of these tumors. This series included 8 groups of endocrinomas: 217 gastrinomas, 76 somatostatinomas, 323 glucagonomas, 873 insulinomas, 163 vipomas, 98 carcinoids, 55 PPomas and 36 miscellaneous endocrinomas. The rate of preoperative diagnosis was significantly higher in the insulinoma group. The head of the pancreas was the predominant site for gastrinomas, somatostatinomas and carcinoids, and the tail for glucagonomas, insulinomas and vipomas. There was a tendency for gastrinomas, glucagonomas and PPomas to be small, 1 cm or less, at detection, and for somatostatinomas and vipomas to be large exceeding 5 cm. The rate of metastases was high in the carcinoids and vipoma groups and significantly lower (6.9%) in the insulinoma group. The syndromes were more often associated with gastrinomas, insulinomas and vipomas, and less often with somatostatinomas and carcinoids. Angiographic detection of the tumor-location showed a consistently high rate, but suggested the efficiency of combined use of other methods, not only imaging but also non-imaging modalities such as venous samplings. |
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