Clinical Gastroenterology Vol.12 No.5(10)

Theme Current Topics in Hepatitis viruses
Title Prevalence of Hepatitis G Virus Infection in Japan
Publish Date 1997/05
Author Yoshiyuki Nakatsuji Second Department of Internal Medicine, Shinshu University School of Medicine
Author Eiji Tanaka Second Department of Internal Medicine, Shinshu University School of Medicine
[ Summary ] Hepatitis G virus (HGV)is a new RNA virus that is most closely related to members of the Flaviviridae family. HGV RNA was found in only a low percentage of patients with either acute or chronic non-A-E hepatitis. HGV appears to be a co-infecting or superinfecting agent in 10 to 15% of HCV infections, and in 5 to 15% of HBV infections. The prevalence of HGV infection(0.8%) among voluntary blood donors in Japan is similar to that for HCV infection. A history of blood transfusion was obtained in 50 to 60% of HGV RNA positive subjects. HGV was also detected in approximately 10% of hemodialysis patients. Finally, isolated HGV infection appears to have a low disease burden.
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