| Theme | Early Esophageal cancer-from the Viewpoint of its Type and the Depth of Invasion | |
|---|---|---|
| Title | Prognosis of Early Esophageal Cancer -- From the Aspects of Clinical Classification and Depth of Invasion | |
| Publish Date | 1997/11 | |
| Author | Hiroyasu Makuuchi | Department of Surgery, Tokai University, School of Medicine |
| Author | Hideo Shimada | Department of Surgery, Tokai University, School of Medicine |
| [ Summary ] | Outcomes of early esophageal cancer were investigated from the aspects of clinical classification and invasive depth. The five year survival rate of superficial esophageal cancer patients treated with radical surgical resection was 85.6%. As for early esophageal cancer, which is limited to within the submucosal layer and has no lymph node metastasis, the rate was 95.4%. If the tumor is limited to within the mucosal layer and the shallow layer of the submucosa, the prognosis is excellent, 100% survival. When the tumor invades to the middle 1/3 or deeper 1/3 of the submucosa, it is poor, 73.5% and 71.6%, respectively. As to clinical classification, 0-IIb and 0-IIa type had a good prognosis with a 100% 5 year survival rate, because the invasive depths of these types of cancer are mucosal, and 0-IIc type, containing mucosal and submucosal carcinoma, a 94.4% 5 year survival rate. The 0-I and 0-III types had a poor prognosis, 77.5% and 72.2%, respectively, because they invaded to the submucosal layer. Endoscopic mucosal resection is indicated for early esophageal cancer, especially mucosal cancer. The outcome of 126 EMR cases was acceptable (100%). Early diagnosis of esophageal cancer, especially mucosal cancer, by endoscopic examination with iodine staining is extremely important not only for determining prognosis but also for the quality of life of patients. |
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